Homolytic substitution at phosphorus for C–P bond formation in organic synthesis
نویسنده
چکیده
Organophosphorus compounds are important in organic chemistry. This review article covers emerging, powerful synthetic approaches to organophosphorus compounds by homolytic substitution at phosphorus with a carbon-centered radical. Phosphination reagents include diphosphines, chalcogenophosphines and stannylphosphines, which bear a weak P-heteroatom bond for homolysis. This article deals with two transformations, radical phosphination by addition across unsaturated C-C bonds and substitution of organic halides.
منابع مشابه
Bond fission in monocationic frameworks: diverse fragmentation pathways for phosphinophosphonium cations.
A series of phosphinophosphonium cations ([R2PPMe3]+; R = Me, Et, i Pr, t Bu, Cy, Ph and N i Pr2) have been prepared and examined by collision-induced dissociation (CID) to determine the fragmentation pathways accessible to these prototypical catena-phosphorus cations in the gas-phase. Experimental evidence for fission of P-P and P-E (E = P, C) bonds, and β-hydride elimination has been obtained...
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